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BMJ Open Sport & Exercise Medicine · 2025

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Ahmad Binmahfoz, Anas Dighriri, Cindy Gray, Stuart R Gray

Effect of resistance exercise on body composition, muscle strength and cardiometabolic health during dietary weight loss in people living with overweight or obesity: a systematic review and meta-analysis

BMJ. 11(3). e002363.

Study type
Systematic review and meta-analysis
Review basis
Full text reviewed

What does resistance exercise add when a person is already following a weight-loss diet? Across 25 trials involving 1,608 adults with overweight or obesity, adding resistance exercise produced little extra change in body weight compared with diet alone. It did, however, favor greater fat loss and preservation of fat-free mass. Strength also improved, although confidence in that estimate was lower. Participants were adults aged 18 to 65, and most programs involved supervised exercise. The findings show why the scale can miss changes that matter when evaluating a weight-loss program.

Fat-free mass includes muscle alongside other tissues and water; it is not a direct measure of muscle alone. Evidence for preserving it was clearer in interventions lasting five months or less than in longer programs. The analysis found no clear additional benefit for several measured cardiometabolic markers. That result concerns the extra effect above dieting and should not be read as a general verdict on exercise and health.

How Does This Show Up in Real Life?

Someone comparing diet alone with diet plus resistance exercise might expect the combined approach to make the scale fall faster. The results suggest that expectation misses much of the possible benefit. A similar weight change can accompany a different balance of fat and fat-free tissue, as well as greater strength. The authors support including resistance exercise in dietary weight-loss treatment for these reasons. The evidence does not identify one universally best routine, and most trials supplied supervision that may be absent from an ordinary home program. Maintaining participation also matters when considering whether a program can work beyond its first months. These findings inform which outcomes to consider, rather than providing a personal exercise prescription.

Confidence was high for greater fat loss, moderate for fat-free mass preservation and low for strength improvement. Programs and measurements differed, and many trials included only women. Longer studies often had substantial dropout or incomplete adherence reporting. Those problems weaken conclusions about sustained benefits; success in a short supervised program does not establish what remains after training stops.

Why We Cite It

Alpekin can use this source when explaining how a treatment comparison should account for function as well as body size. It also provides a practical example of grading confidence separately for each outcome, instead of treating every conclusion in a single research paper as equally certain.

The evidence supports a useful role for resistance exercise within the studied setting. Expectations should reflect both the outcome being measured and the support needed to sustain the program. Longer-term results deserve more caution than the stronger short-term body-composition findings.

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