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Sports Medicine · 2023

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Isabel G Martinez, Alice S Mika, Jessica R Biesiekierski, Ricardo J S Costa

The Effect of Gut-Training and Feeding-Challenge on Markers of Gastrointestinal Status in Response to Endurance Exercise: A Systematic Literature Review

Springer Science and Business Media LLC. 53(6). 1175-1200.

DOI PMID: 37061651 Open original source
Study type
Systematic review
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Full text reviewed

Eating during endurance exercise can provide useful fuel while also causing digestive discomfort. Repeated practice with food or drinks may help, but the evidence does not show that every part of digestion adapts. Eight studies examined repeated feeding before or during exercise, using interventions lasting 4–28 days. In one study of 18 male runners, gut discomfort fell by 48% after two weeks of carbohydrate-feeding practice, compared with 20% in the placebo group. That result belongs to one trial. Differences between the studies prevented the researchers from calculating a pooled effect.

Less discomfort does not necessarily mean faster stomach emptying or a stronger intestinal barrier. The studies assessing those outcomes did not show clear improvements. Some found reduced carbohydrate malabsorption, assessed using breath testing, but results were not uniform. Findings for digestive symptoms were mixed, and higher carbohydrate intakes could worsen symptoms in some highly trained athletes. The amount consumed and the athlete's previous feeding experience may matter.

How Does This Show Up in Real Life?

A fueling plan has to be tolerable as well as nutritionally suitable. For an endurance athlete, this evidence supports considering repeated practice with the intended food or drink around training, rather than assuming that an unfamiliar race-day intake will be comfortable. However, the research does not establish one ideal quantity, product, or practice schedule. Some study protocols used large carbohydrate intakes to challenge the gut; those amounts describe the experiment and are not universal targets. It also helps to distinguish the goal being claimed. Becoming more comfortable taking fuel during a run is different from preventing exercise-related intestinal injury, and the latter was not demonstrated. The results are most relevant to endurance exercise and feeding tolerance. They do not establish a treatment for digestive disease or show that persistent symptoms outside exercise can be managed by simply eating more during training.

The evidence base was small and mostly male, with participants generally aged 15–35. Studies used different symptom questionnaires, feeding methods, and exercise conditions, making comparison difficult. Some had concerns about bias. The short interventions did not establish how long any benefit would last after practice stopped. More evidence is needed before a reliable, broadly applicable gut-training prescription can be given.

The findings justify cautious interest in practicing exercise fueling, with attention to individual tolerance. Confidence is greater for the possibility of symptom improvement than for claims about intestinal protection. A successful result in one feeding trial should not become a promise for every athlete.

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