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Ferritin

Ferritin stores iron within cells, while blood levels help assess the body's reserves but can also rise with inflammation or infection.

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Ferritin is an iron-storage protein found within cells. Its concentration can also be measured in blood .1

The concentration of ferritin in blood is used as an indicator of the body's iron stores. In the absence of inflammation, blood ferritin generally increases as those stores increase. A low concentration indicates depleted stores .1

Ferritin also rises during inflammation and infection, so its blood concentration does not always track iron stores reliably. Liver disease and other conditions can raise it as well. Consequently, a high ferritin result alone does not establish iron overload. Understanding the measurement requires distinguishing ferritin's role as a storage protein from the factors that change its concentration in blood .1

References

  1. World Health Organization WHO guideline on use of ferritin concentrations to assess iron status in individuals and populations. 2020. About this source Original source

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