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Oral Microbiota

Oral microbiota form interacting communities in the mouth, where local conditions shape how resident microorganisms contribute to oral health.

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Oral microbiota are the microorganisms that inhabit the mouth. Bacteria are a major component, but the community also includes fungi, archaea, and associated viruses. These organisms form a normal part of the oral environment, rather than being present only when infection or disease occurs .1

The mouth contains several distinct habitats, including tooth surfaces and the soft tissues lining the oral cavity. Many resident microbes live in biofilms, organized communities attached to surfaces. Within these communities, microbes interact through cooperation, competition, and chemical signaling. The oral microbiota are therefore an interacting ecosystem, not simply a list of individual species .2

Resident communities can help resist colonization by disease-promoting microorganisms and contribute to normal oral functions. Their relationship with the host depends on both the organisms present and the conditions in which they live. Diet, saliva, and other features of the local environment help shape these communities .1,2

A disruption in community composition or activity is often called dysbiosis. Such shifts can favor processes involved in tooth decay or gum disease .2

References

  1. Rajasekaran JJ, Krishnamurthy HK, Bosco J, Jayaraman V, Krishna K, Wang T, Bei K Oral Microbiome: A Review of Its Impact on Oral and Systemic Health. Microorganisms. 2024. About this source DOI
  2. Kilian M, Chapple IL, Hannig M, Marsh PD, Meuric V, Pedersen AM, Tonetti MS, Wade WG, Zaura E The oral microbiome - an update for oral healthcare professionals. British Dental Journal. 2016. About this source DOI

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